Cell biology of antigen presentation
Identifieur interne : 004589 ( Main/Exploration ); précédent : 004588; suivant : 004590Cell biology of antigen presentation
Auteurs : Jacques J. Neefjes [Pays-Bas, Allemagne] ; Frank Momburg [Pays-Bas, Allemagne]Source :
- Current Opinion in Immunology [ 0952-7915 ] ; 1993.
English descriptors
- Teeft :
- Absolute requirement, Acad, Anchor residues, Antigen, Antigen presentation, Antigen processing, Bind peptide, Cell biology, Cell line, Cell surface, Cell type, Class class, Cytoplasmic antigens, Degradation, Degraded, Degraded antigen, Empty class, Endocytic, Endocytic pathway, Endocytic route, Endoplasmic reticulum, Exogenous, Exogenous peptides, Free class, Heterodimer, Heterodimers, Histocompatibility, Histocompatibility molecules, Intact cells, Intracellular, Intracellular transport, Invariant chain, Lysosomal compartments, Major histocompatibility, Major role, Miic class, Molecule, Molecules bind peptides, Murine class, Mutant cell line, Neefjes, Nuclear peptides, Nuclear proteins, Pathway, Peptide, Peptide antigen, Peptide binding, Peptide binding groove, Peptide generation, Peptide loading, Presentable, Presentable peptide, Presentable peptides, Proc, Proc nat1 acad, Protease, Proteasome, Proteasome subunits, Reticulum, Self peptides, Signal sequences, Specific antigen, Spleen cells, Stable surface expression, Subunit, Surface expression, Transporter, Unpublished data, Variant chain, Viral antigen.
Abstract
Abstract: MHC class I molecules present degradation products derived from intracellular proteins, whereas MHC class II molecules generally present peptides derived from extracellular or surface proteins. Recent insights into the cell biology of MHC class I and II molecules explain this difference.
Url:
DOI: 10.1016/0952-7915(93)90077-6
Affiliations:
- Allemagne, Pays-Bas
- Bade-Wurtemberg, District de Karlsruhe, Hollande-Septentrionale
- Amsterdam, Heidelberg
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Le document en format XML
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<term>Antigen processing</term>
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<front><div type="abstract" xml:lang="en">Abstract: MHC class I molecules present degradation products derived from intracellular proteins, whereas MHC class II molecules generally present peptides derived from extracellular or surface proteins. Recent insights into the cell biology of MHC class I and II molecules explain this difference.</div>
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